Of the 1,583 loci with alternative splice forms represented on the array, about 95% (1,496) were expressed well over background, according to at least one oligo.
Both isoforms were expressed well with hGPR17-S being present at approximately 30 40% higher levels than hGPR17-L at corresponding doses.
As expected yeasts expressing AtAMT1 2 grew well at any pH and yeasts expressing K10 allowed a good complementation at pH 7,25.
Figure 3 shows that time-0 BZ markedly accelerated BCR/Ablprotein suppression occurring in untreated hypoxic cultures [1], [3], where BCR/Ablprotein was still well expressed at day 2. BZ treatment at day 1 failed to determine such an effect, indicating that a one-day incubation in hypoxia protected BCR/Ablprotein from BZ-induced suppression.
We conclude that KCNQ3 homomers are well expressed at the plasma membrane, but that most wild-type channels are functionally silent, with rearrangements of the pore-loop architecture induced by the presence of a hydroxyl-containing residue at the 315 position "unlocking" the channels into a conductive conformation.
A differentiation is also well expressed at a super-familial level as both Cavioidea [25] and Octodontoidea members [26] occupied variable positions in the morphospace of the mandibles.
We found that HLA class I was always well expressed at the melanoma cell surface, in some istances in amounts comparable to autologous lymphocytes.
In particular, we have shown how AID 57 and 59 are well expressed at the protein level, while AID 50 is not, although its mRNA is abundant.
As an internal control, membranes were incubated with antibodies recognizing the GAS surface protein Spy0269, which was found to be equally well expressed at pH 7.5 or 6.4 by real-time reverse transcription PCR (RT-PCR, data not shown).
The Lpat471 construct is soluble and well expressed at both 20°C and 37°C, suggesting that this truncated form of Lpa could be an improved tool over wild type Lpa for probing α-ketoacid dehydrogenase inactivation in vivo.
