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At later stages, when other markers for hair cells are expressed, we found Fgf8 expression in the ganglia in a pattern reminiscent of the hair cells identified by other markers (Fig. 3 E').
By applying Fisher's exact test to identify enriched KEGG pathways among those genes called differentially expressed, we found 6 KEGG pathways to be over-represented among the identified genes.
When using probability 0.8 (means that the feature is four times more likely to be differentially expressed than non-differentially expressed) as the threshold for each gene of being differentially expressed, we found 1080 (Fasting) to 1739 (LPS) genes were differentially expressed between treatments and the respective controls (Table 2).
By analyzing reads from 79 miRNAs where the miRNA* was also expressed, we found the opposite to be true: the 5' end in a cleavage end pair was significantly less variable than the 3' end and this was true for both miRNA (p = 1.2 E - 11, Wilcoxon rank-sum) and miRNA* 5' (p = 5.9 E - 13) ends.
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Conversely in HEPG2 cells where a high level of HNF4A is expressed, we find very low expression of let-7 family miRNAs.
Even though most novel TARs seem to be lowly expressed, we find a few interesting instances among these.
Our numerical results demonstrate that by applying our hypothesis to the data (transcriptional regulatory network and the reference list of genes known to be periodically expressed) we find a subnetwork of the overall transcriptional regulatory network connecting almost 80% of all periodic genes in the WCC.
Later, the same note returns: "Open spaces bring to the mind something which is difficult to express"; "we find it hard to make language grip landscapes that are close-toned".
When co-expressed, we found intracellular reporter fluorescence to be correlated with cell-specific antibody secretion at the population level [44], and with 'cold capture' cell surface antibody [46] at the single-cell level (Fig. S1).
While examining the set of abundantly expressed genes, we found, surprisingly, that Bergmann glia express mRNA for the myelin protein peripheral myelin protein (Pmp22) and for myelin protein zero-like 1 (Mpzl1), which may be important for myelination [35] (Table S4).
According to the screening criteria of differentially expressed miRNAs, we found that 321 novel miRNAs were differentially expressed in two wheat genotypes after dehydration stress (Additional file 3: Table S3).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com