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Although the PD1-CD2/Bam micexpresseded surface CD2 on PBL, the patterns of expression of the CD2 transgene on lymphocyte populations and in the tissues differed markedly from the endogenous MHC class I and PD1 transgene patterns (Figure 2B; data not shown).
We found that Foxp3+ Tregs expressed surface LAP and that surface LAP is induced by forced expression of Foxp3 or by TGF-β irrespective of Foxp3 induction.
Chimeric antigen receptors (CARs) can effectively redirect cytotoxic T cells toward highly expressed surface antigens on tumor cells.
Molecular analysis revealed that relapsed tumors harbored nonmutated antigen genes, not silenced by promoter methylation, and functionally expressed surface antigen at levels equal to nontreated tumors.
These AML-004 cells lacked specific markers for B and T lymphoid cells, but expressed surface receptors for lymphoid/NK cells.
The binding of these labeling antibodies to poorly expressed surface antigens may preclude their activation and underestimate cytokine production and their response to various stimuli including LPS [16].
Similar(11)
In this respect, only P. acnes expressed surface-attached endoglycoceramidases, which might hydrolyze gangliosides on host cell membranes [ 43].
In contrast to controls that show no MPO surface expression, all patients with polyarticular JRA demonstrated a subpopulation of neutrophils (10% to 23% of the cells) that expressed surface-associated myeloperoxidase.
Green Unlabeled human nasopharyngeal epidermal carcinoma cell line over-expressing surface receptors for folic acid.
While not all subsets of BCP-ALL cells express surface pre-BCR, most express components of the pre-BCR intracellularly.
These results suggest that monocytes express surface ERBB3.
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