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The fact that these 4094 genes were predicted as miRNAs targets but not significantly differentially expressed, suggested that the expression of these 4094 mRNAs might not be regulated by the 32 dysregulated miRNAs, but by other mechanisms such as regulation by other miRNA, methylation, cis-regulatory elements, etc. which may act and counteract the regulation of miRNA.
Less stringent bioinformatic searches of inverted repeat motifs found upstream of genes that were differentially expressed suggested the possibility of an energy regulon in Cand.
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We observed an increase of PPARα expression when NOX1 was not expressed; suggesting that NOX1 activity constitutively represses PPARα expression.
In 11/13 cases only the mutant alleles were expressed suggesting loss or reduced expression of the wild type alleles in these cases.
On average (in regions with at least 5 probesets), 50% of the probesets were found to be differentially expressed suggesting a generalised increase in expression of genes within CN gains.
The results implied that hub proteins in CePINs are more likely to be differentially expressed, suggesting modular rewiring of co-expressed interactions between different biological states.
Taken together these results suggest that expression of NF90ctv drastically curtails the amount of p24 expressed, suggesting inhibition of HIV-1 particle production.
That such doubts are now being expressed suggests that opponents are succeeding in shifting the debate, if not necessarily winning it.
This view, though not lucidly expressed, suggests Siger's disregard for doctrines of the church and his emphasis on maintaining the autonomy of philosophy as a self-sufficient discipline.
Both OsPIP1 2 and OsPIP1 1 are ubiquitously expressed suggesting functional redundancy between the two.
The finding that several MAGE genes are ubiquitously expressed suggests a role for MAGE encoded proteins in normal cell physiology.
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