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3 log2forfor the corresponding comparison in which the gene was identified as being differentially expressed (significant at FDR < 0.05) positive log2FCs reflect higher expression values in Condition2 whilst negative log2FC refer to higher expression in Condition 1 of specific comparisons (cf Table 1).
bThe putative target genes of miRNA genes which differentially expressed significant at 0.05 level between the mutant and wild type High ranked target genes of the differentially expressed miRNAs were those implicated in three biological processes including regulation of transcription, protein modification and photosynthesis.
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They expressed significant anxiety and discomfort at what they considered an alien environment.
However, the N10 populations expressed significant heterosis in total fitness at intermediate (f = 0.30 and f = 0.34), but not at low (f = 0.17), or at high levels of inbreeding (f = 0.45 0.70).
The correlation between the latent variables of the model (Bartlett test of sphericity = 137.5 with 9 df, p < 0.0001) confirmed, moreover, the appropriateness of the choices made for the multivariate data analysis (it was all further supported by positive results from Pillai's test, Hotelling's T2, Wilks' lambda, all expressing significant values at the level p < 0.000).
It has also been shown that some MICA expressing melanoma cell lines do not necessarily express significant levels of MICA at the cell surface[46].
While quiescent microglia do not express significant levels of these molecules at steady state, both MHC-I and MCH-II are upregulated in activated microglia, which also express co-stimulatory molecules such as CD40 and CD80/86 [ 71, 133].
The level of significance was expressed as significant at P < 0.05 and highly significant at P < 0.01 [ 31].
We considered probes as differentially expressed when significant at a 5% FDR.
Although remaining neuroligins are expressed at significant levels their expression is not obviously linked with sensory response possibly because these have modulating roles including specifying inhibitory synapses that act to filter or adapt sensory experience.
A comparison of expression level revealed that two segmental duplicated genes in one pair always showed similar expression pattern, although one of the duplicated genes showed low expression level, or was not expressed at significant levels in most of the tissues.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com