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It is evident that there is a subset of breast- and prostate cancers where most genes in the SOG pathway are highly expressed, resulting in a significant expression of the SOG gene signature.
The immunohistochemical and kinetic data included in this study indicate that in the transitional tissue ST6Gal I is indeed expressed, resulting in a significant percentage of cases with positive expression for the CDw75 antigen.
This rough-eye phenotype was more severe when PAR-1 was also expressed, resulting in a reduction of the S11A eye size (Fig. 6H).
We made the assumption that if a VH and a VL were expressed when associated respectively with the VL13R4 and the VH13R4, the scFv constituted with these VH and VL would also be expressed, resulting in a library containing only expressed scFvs.
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NKN2-2 was not consistently expressed in all passages of NT2 cells and when expressed resulted in a Ct of 40 or greater (data not given).
We found that the depletion of BMI-1 in SAOS-2 cells, in which BMI-1 is highly expressed, resulted in an increased sensitivity of these cells to cisplatin.
If the extract of aquatic sample B has weak demethylation potential, the methylation level will be almost unchanged and very little green fluorescence protein will be expressed, resulting in the observation of a light green fluorescence.
An RPKM (Reads per Kilobase per Million reads) cutoff value of 0.1 was set to declare a locus expressed, resulting in 21,530 loci above the expression threshold.
An RPKM (Reads per Kilobase per Million) cutoff value of 0.1 was set to declare a locus expressed resulting in 31,666 loci above the expression cutoff in at least one genotype.
An RPKM (Reads per Kilobase per Million) cut-off value of 0.1 was set to declare a locus expressed resulting in 32,862 and 32,778 loci above the expression cut-off for Eurosis and Loto varieties, respectively.
This work shows that miRNAs preferentially target messages that are highly connected and when aberrantly expressed results in a loss of cell cycle control leading to increased proliferation, invasion and metastasis.
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