Sentence examples for expressed regulation from inspiring English sources

To address these two challenges, we present a novel approach called Differentially Expressed Regulation Analysis (DERA).

We used T value of 50, i.e., a differentially expressed regulation was required to be found and to be identical in at least 50% of the sample-specific regulation networks in order to be classified as a core regulation.

Even using stringent threshold 0.5 for validation set (default cut-off T was 0.4, i.e., a differentially expressed regulation was required to be found and to be identical in at least 40% of the samples), out of 95, 87 differentially expressed regulations were validated (Additional file 1: Figure S8).

We present a novel network method, Differentially Expressed Regulation Analysis (DERA) that integrates expression data to biological network information at a single sample level.

Venn diagram of differentially expressed regulations in different TNBC cohorts and their overlapping regulations.

Venn diagram of differentially expressed regulations in HGS-OvCa discovery and validation sets, and their overlapping regulations.

The DERA analysis identified 95 differentially expressed regulations that were composed of 101 genes (Additional file 1: Figure S6).

All of these 95 differentially expressed regulations were validated in the validation set (Additional file 1: Figure S7).

The distinctive advantage of BNKL - its utility in discovering differentially expressed regulations between comparable conditions - has been applied for discriminating cancer sub-types.

Of the 95 differentially expressed regulations DERA identified in HGS-OvCa four regulations consisting of eight genes were also present in the set of 22 regulations (consisting of 30 genes) found to be unique in TNBC by DERA.

Although ubiquitously expressed, the regulation of STS expression does appear to be tissue specific and is subjected to various feedback mechanisms, such as that shown by the positive correlation between STS and estrogen receptor (ER) isotypes mRNA (52).