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202 tags were found differentially expressed (p < 0.05, and fold change >2) between PDLLA and MPLA LongSAGE libraries.
517 and 1358 genes were differentially expressed, p < 0.05, respectively in cardiomyocytes treated with trastuzumab and lapatinib.
76/11,466 (0.66%) genes expressed in both cell types were differentially expressed, p < 0.05, (Additional file 2: Figure S1B).
76 genes were differentially expressed, p < 0.05 in both cancer cell lines and iPSC-derived cardiomyocytes following treatment with trastuzumab (Table 1).
For each transcriptome, we took those genes differentially expressed, p < 0.05 and searched for enrichment of gene ontology categories by biological process.
Furthermore, genes responsible for pro-apoptotic end functions such as DNA degradation (DFFB: 1.87-fold under expressed, p = 7.63×10−6) and caspase cascade initiation were significantly under expressed (FADD: 1.54-fold under expressed, p = 3.9×10−5).
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The test for differential expression gives only six cliques as differentially expressed (p-value ≤ 0.05, see Table 2).
The test for differential expression repeated on each clique gives 13 cliques as differentially expressed (p-values≤ 0.1).
The expressed P-JEV showed reactivity in in vitro assays with JEV monoclonal antibodies.
Also, highly expressed p-JNK, p-ERK, p-p38, p-NF-κBp65, p-IκBα, p-IKKα and p-IKKβ in MI rats were restored respectively by DGBUT treatment.
In developing lung, most (but not all) E-cadherin-expressing developing bronchi also expressed P-cadherin (Fig. S1B).
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