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However, these experiments were performed with only one serotype that expressed only a single member of the M protein family (i.e., pattern A) and the possibility that LTA might form complexes with other proteins was not investigated.
RNA-DNA FISH showed that the majority of single cells expressed only a single allele.
Transgenic mouse strains were backcrossed with Rho−/− mice so that these rods expressed only a single type of rhodopsin (Lem et al., 1999).
In contrast, in our previous deletion experiments hybrids expressed only a single endogenous copy of either mel-Lhr or sim-Lhr.
In some species, GH 45 genes have rapidly propagated and diversified (e.g. Leptinotarsa decemlineata), while in other cases, the insect expressed only a single copy of this gene (e.g. G. viridula and C. tremulae).
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Individual IEs express only a single PfEMP1 variant at a time [12].
It has been postulated that zebrafish slow muscles express only a single MyHC isotype [20], [21].
Unlike humans who express only a single hepcidin gene, mice express two isoforms of hepcidin, Hepcidin 1 (Hand1) and Hepcidin 2 (Hamp2).
The serotypes tested ranged from those that express only a single M protein gene to those that express two or three members of the M protein family.
Inactivation of emm in those serotypes expressing only a single emm gene reduced biofilm formation, and protein-bound LTA on the surface, but did not alter the levels of membrane-bound LTA.
The complex mechanisms that control c-myb gene expression must not play a role, and the results cannot be due to different activities of variant isoforms produced through alternative RNA splicing, since the lentivirus vector expresses only a single, full-length cDNA of c-Myb and is not subject to the controls that regulate c-myb gene expression.
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