Expression of exogenous Prdx1WT reduced colony formation by 50% in Prdx1−/−;H−Rand12MEFs and by 20% in Prdx1+/+;H−RasV12MEFs, whereas exogenously expressed Prdx1C51/172S modestly increased colony formation in Prdx1−/−;H−RasV12MEFs and Prdx1+/+;H−RasV12MEFs.
It is noteworthy the significantly lower expression of MtGS1b, relatively to MtGS1a and MtGS2a, in most organs and conditions tested, being expressed at modestly higher levels in roots and flowers.
In the comparison between the un-annotated TE exons (C4) and the simulated exons (C5), 20 of the 26 samples have a p-value less than 0.01, indicating that the un-annotated TE exons (C4) are expressed at modestly higher and significant levels in most tissues.
Lysates of the LRIG2 and LRIG3 expressing cells modestly produced the full-length protein (Figure 4A B, left panels), with LRIG2 being present in multiple bands likely arising from differential glycosylation.
However, DISC1 was modestly expressed in hESCs and the expression decreased after neural differentiation, suggesting that DISC1 might play an important role in stem cell functions.
Two repressors of seed maturation genes, ASIL1 (ARABIDOPSIS 6B-INTERACTING PROTEIN 1-LIKE 1) [ 69] and PICKLE (PKL) [ 70], were modestly expressed and exhibited a stable expression pattern throughout seed maturation.
Among the genes related to apoptosis, we noted that the genes encoding caspases, the main effector molecules in ovarian apoptosis, were only modestly expressed in the infant ovary and their expression increased in variable degrees in the adult ovary.
In addition, members of the Bcl gene family, including Bcl2, Bax, Bok, Bcl2l1, Bcl2l2 and Bad, were all modestly expressed in the infant and adult stages, although expression of some genes including Bad and Bok was slightly upregulated in the adult.
As the general manager of the elegant Mayflower Inn, John Trevenen, put it, "There's a lot of money here, but it's modestly expressed".
