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Even so, in the periphery, the expressed light chain may also be inactivated by somatic mutation, and an autoreactive light chain can be re-expressed [ 91].
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We compare biophysically and energetically the cellular responses to direct electrical current injection versus optical stimulation mediated by genetically expressed light-sensitive ion channels, e.g., Channelrhodopsin-2 (ChR2).
To examine this possibility, we utilized mice expressing Cre-recombinase under control of the endogenous choline acetyltransferase locus and conditionally expressed light-activated Channelrhodopsin2 in CINs.
We prepared phage libraries expressing LIGHT mutants in which all the lysine residues were replaced with other amino acids.
Many resultant hybridomas express one of several myeloma kappa chain transcripts, even though the parent myeloma may have been ascribed as not expressing light chain protein.
Depending on the instrumentation used, different units are used to express light intensity.
In studies that express light intensity in RLUs, the detection limit is often defined as the concentration that leads to a significantly higher luminescence compared with the control [ 68].
We demonstrated that CaMKII expressing (light responsive) pyramidal neurons can be classified into phasic and nonphasic based on the periodicity revealed in the autocorrelation histogram of their firing pattern and this too is novel.
By Ted Hughes The New Yorker, June 24 , 1974P. 42 After the brown harvest of rains, express lights View Article By Miranda Carter By Amos Barshad By Emily Nussbaum By Doreen St. Félix.
By Ted Hughes The New Yorker, June 24 , 1974P. 42 After the brown harvest of rains, express lights View Article By Jelani Cobb By David Remnick By Jia Tolentino By Yasmine Al-SayyaDavid Remnick By Jia Tolentino By Yasmine
One strategy to restore light responsiveness to a retina rendered blind by photoreceptor degeneration is to express light-regulated ion channels or transporters in surviving retinal neurons.
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