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Forced expression of the transcription factors Oct4, Sox2, Klf4, and c-MYC induced formation of cell colonies that were indistinguishable from those of control mouse ES cells (Fig. 1 A, G ). Immunocytochemical analysis revealed that dsRed-iPS cell colonies expressed levels of the markers Oct4 (B), c-MYC (C), Sox2 (D), Nanog (E) and Klf4 (F) that were comparable to mouse ES cells (G, H, I, J&K).
The CMS-associated GMPPB mutations that we describe are predicted to be pathogenic by several different algorithms, and several cause a distinct reduction in the expressed levels of the protein.
So compared to 15 DAF, the differentially expressed levels of the gene encoding KASIII at 35DAF, 55DAF, 65DAF negatively correlated to fatty acid synthesis during the seed development, which is consistent with previous research [ 23].
The increase in proliferation was not accompanied by the loss of differentiated β-cell phenotype since knockout tissues expressed levels of the maturation markers Glut2, Mafa, Mafa and Nkx6.1 similar to those of the heterozygote (supplementary material Fig. S12D).
Unlike other methods that integrate gene expression information only to infer the modular network structures [ 9], we also used the differentially expressed levels of the modules as a tool to screen the modules most likely influenced by drivers, to characterize those core modules, and to identify mutations enriched in the modules.
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The detection threshold cycle for each reaction was normalized against the expressed level of the rice reference gene ACT1 (GenBank ID: AK100267) [ 58].
However, the expressed levels of Nestin were reduced compared with neurospheres, which expressed high levels of Nestin.
The expressed levels of satisfaction were similarly high when women were asked direct and indirect questions.
Different forms of Se exposure induced the different expressed levels of TCPZ and hnRNP-F in Caco-2 cells.
a Detection of the expressing level of COX-2 and VEGF-C by immunohistochemistry. b Intensity of immunohistochemical staining.
In our study, the expressing level of adipsin was under-represented in diabetic serum.
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