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Like DELLA-domain proteins, the homologs of RGA (Cj 552_1, 1674_1) were expressed inversely to these genes.
Analysis of mRNA coding genes and miRNAs displaying these two trends showed that miRNAs were expressed inversely to their highly expressed predicted targets.
Genes expressed inversely to regulons 1 and 2 included those involved in protein synthesis as well as a various membrane transporters.
Additionally, TTF-1 is reported to be expressed inversely in relation to tumour differentiation (Lau et al, 2002; Jagirdar, 2008; Yang and Nonaka, 2010).
27, 28 The existing methods do not necessarily optimize the correlation of biclusters, and some biclusters derived from other algorithms can contain biclusters showing strong anti-correlation (ie, genes expressed inversely).
Thrombospondin-1 has been shown to promote follicular atresia in rats [ 55], and together with thrombospondin-2 is expressed inversely with VEGF in a cyclical fashion during folliculogenesis in cows [ 52].
Similar(53)
Samples were analyzed by Western blotting, Figure 1D showed that increased amount of expressed BCA2 inversely correlated with the expression of 14-3-3σ 14-3-3σ 14-3-3σ
Since miRNAs cause degradation of their target mRNAs, the two express inversely (Raghuram et al. 2014).
Furthermore, protein data of inversely expressed Bax and Bcl-2 protein expression were confirmed by additional analysis of Bax and Bcl-2 mRNA expression using real-time PCR (data not shown).
The RB protein was expressed in about half (44%) of OSCCs and its expression inversely correlated with p16/MTS1 expression.
The inhibition of miR-214 has been also correlated with decreased apoptosis and miR-214 and PTEN were indeed inversely expressed, while knockdown of miR-214 altered the expression of PTEN and p-AKT, resensitizing HCC827/GR to gefitinib.
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