Sentence examples for expressed in targeted from inspiring English sources
"Optogenetic" silencers, genetically encoded molecules that, when expressed in targeted cells within neural networks, enable their electrical activity to be quieted in response to pulses of light, are enabling these kinds of causal circuit analyses studies.
We next investigated whether catalytically active RdRp expressed in target cells (trans expression) could rescue infectivity of RdRp-deficient or RdRpcat1 RVF-VLPs.
However, after one round of retroviral replication, the intervening sequence should be removed by the cellular machinery and the therapeutic gene will be selectively expressed in target cells.
After ADC molecules are administered into the blood stream, the antibody component of the ADC recognizes and binds to cell-surface antigens that are highly expressed in target cancer cells.
Normal-length and elongated versions of Cw6 and MICA fused to GFP or mCherry [58] were expressed in target cells using lentiviral transduction.
However, we demonstrated that one line, UAS-Ni-14E (hereafter referred to as UAS-Ni) effectively reduced the accumulation of Notch protein (as judged by western analysis) and eliminated Notch signaling when expressed in target tissues [16].
Other proteins differentially expressed in target tissues of CF before the appearance of any sign of the disease, like annexin-1 (also found cleaved in the sputum of CF patients) [10], cytosolic phospholipase A2α [10], cytokeratins 8 and 18 [11], peroxiredoxin 6 [12] may also be part of a proteomic signature.
Various autoantibodies reactive with epitopes expressed in target organs have been detected in the sera from patients with autoimmune disease [ 1, 8- 11].
When pUL135 was expressed in target cells, ISs were less common, their morphology was less defined, and actin polymerization at the IS was much reduced.
Optogenetic constructs are typically expressed in target cells using strong promoters and multiple copies of viral genomes to achieve high level of expression.
Both non-MHC and MHC polymorphisms associated with susceptibility predispose the TCR repertoire to auto-reactivity and recognition of target self-peptides that are likely to be expressed in target tissues.
