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Moreover, some miRNAs were strictly diet-specific; these miRNAs, although not differentially expressed, exhibited peculiar characteristics in which they were expressed either in response to chow diet but not HCHF diet, or vice versa (Additional file 3: Table S2).
Insertion of Trp at positions V91, Q92, and A94, which all map to the neck of the pore, generated channels that were expressed, exhibited some protection against downshock, but failed to exhibit currents despite the observation of MscL channels in the patches (Table 1 ).
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Despite having statistical support, approximately 6% of the signatures with significant differences in expression would nonetheless be considered constantly expressed, exhibiting expression ratios < 2 (Table 2, Figure 4).
respiration ψ indicates previously published data (Palladino et al. 2003), – indicates not tested The Na+, K+ ATPase is known to be broadly expressed, exhibit high expression in the neuromuscular system and be a major consumer of cellular energy.
However, the expression of G464R-hSyn II was unable to correct the KO phenotype, indicating that this mutant, albeit normally expressed, exhibits a developmental loss-of-function.
The expression patterns of transcripts identified as differentially expressed exhibit the same patterns in the qPCR validation; over all loci tested, the relationship between the two methods was positive and significant (r = 0.632, P < 0.001, Figure 7B).
Genes were defined as differentially expressed exhibiting at least a 1.5 difference in expression changes in infected lungs of C57BL/6J and DBA/2J.
MiRNAs with high fold changes that are not differentially expressed exhibit a too high biological variance within the groups to reach the significance threshold.
For people who geek out over Superman or "Star Wars," there are many conventions and opportunities to express, exhibit and indulge their fandom — perhaps the best known being the annual Comic-Con in San Diego.
Remarkably, >30% of the differentially expressed genes exhibited a male or female expression bias.
Only those transcripts were considered as differentially expressed which exhibited two fold or above differential expression.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com