Sentence examples for expressed disease from inspiring English sources
We also showed that expressed disease genes tend to be more functionally similar if the disease manifests itself in that tissue.
This example supports our hypothesis that a disease manifests itself only in tissues in which the expressed disease genes form a disease module, i.e., a statistically significant connected subgraph.
For comparison we also show the subnetwork of tauopathies-related genes in endothelial cells and lymph nodes, where the expressed disease genes do not form a significant connected component, a pattern characteristic of the remaining 60 tissues (Fig. 3H,I).
Because of the partial nature of genotypic resistance or the increasing resistance against fungicides, the tolerance, i.e. maintaining yield in the presence of expressed disease, is a relevant alternative.
In addition, we annotate the functions and biological pathways associated with RPE expressed (disease) genes.
These proposed criteria would improve the sensitivity in the detection of early or incompletely expressed disease.
The tissues with the largest number of expressed diseases are BDCA4 dendritic cells (18 diseases), X721 B lymphoblast cells (16 diseases), and CD56 NK cells (12 diseases), appearing as the hubs of the disease-tissue network.
Proteasome inhibition also accelerates or promotes the aggregation of ectopically expressed disease-specific proteins like huntingtin and α-synuclein [11], [22].
While array analysis of PBMC provides some useful information, the use of purified cell subsets identifies many more differentially expressed disease-specific genes.
For each disease, we compared the proportion of expressed lncRNAs (>2 RPKM) in the whole genome (genome-wide, gray) with the proportion of expressed disease-specific lncRNAs (red), and tested for differences using two-tailed Fisher's exact test.
For each disease, we compared the proportion of expressed coding genes (>2 RPKM) in the whole genome (genome-wide, gray) with the proportion of expressed disease-specific coding genes (red), and tested for differences using two-tailed Fisher's exact test.
