As the two 6S RNAs, tmRNA was highly expressed consistent with its role in recovery from a variety of stresses and interestingly both, 6S2 RNA and tmRNA, showed evidence of antisense transcription (Table S8).
Arginine butyrate-treated mice gene expression profiling experiments revealed that several genes that control cell proliferation, growth and differentiation are differentially expressed consistent with its histone deacetylase inhibitory activity when compared to control (saline-treated) mdx mice.
However, after 24 h, when FA concentration was high, the DGA1 gene was strongly expressed, consistent with the major contribution of its product to TAG formation.
Whereas BCL2 and MCL1 were differentially expressed, consistent with our previous report [ 46], all 3 cell lines expressed BCL2A1.
Furthermore, genes involved with transcriptional regulation and DNA/RNA binding are also differentially expressed consistent with potential gene silencing processes.
The results demonstrated that all the 5 selected genes were clearly expressed in trichomes, 3 were highly expressed and 2 were weakly expressed, consistent with the microarray data.
Interestingly, a sole oligosaccharide ABC transporter-specific ATP-binding protein was identified in the genome and found to be constitutively highly expressed, consistent with a single ATP-binding protein energizing multiple oligosaccharide ABC transporters as previously described [ 56].
Our study shows similar results in the expression levels of Olfr genes with Magklara et al. (2011), that is, Olfr genes are lowly expressed, consistent with the "one neuron one receptor" hypothesis Overall, our study has detected more expressed Olfr genes than the previous studies and has identified Olfr genes and novel duplicate Obp genes that are expressed differentially between the two sexes.
However, after 24 h, when FA concentration was high, the DGA1 gene was strongly expressed, consistent, again, with its major contribution to TAG formation.
These biochemical data indicate that NPC1L1 exists as a predominantly cell surface membrane expressed protein, consistent with its proposed role as the putative intestinal sterol transporter.
In contrast, Kit+ SGs expressed Stra8, consistent with its role in committing SGs to meiosis.
