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The HER2-negative cases with strong pHER2 expression were in 82% of cases expressed concomitant with pHER1 and/or pHER3.
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Others express the concomitant concern of increased competition in the U.S. job market due to the steady influx of internationally trained scientists who dominate the current workforce (Campbell, 2000; Hurtado et al., 2009; National Academy of Sciences, 2011).
In line with these results, we have found diminished JNK activation in keratinocytes expressing CYLDWT, concomitant with an enhanced epidermal differentiation of the CYLDWT skin equivalents; additionally, we have found increased JNK activation in the CYLDC/S keratinocytes associated to an impaired epidermal differentiation of the CYLDC/S skin equivalents.
In our analysis series, there were no polySia-expressing tumors, which did not show concomitant and colocalized NCAM expression.
Microarray experiments are often performed with a small number of biological replicates, resulting in low statistical power for detecting differentially expressed genes and concomitant high false positive rates.
A previous study reported that microarray experiments were performed with a small number of biological replicates, resulting in low statistical power for detecting differentially expressed genes and concomitant high false-positive rates.
Since, first, MMP1 processing is in part dependent on MMP3, second, these MMPs present partially distinct substrate specificities, and, third, none of their tissue inhibitors was found over-expressed, concomitant increases of MMP1 and MMP3 in patients' fibroblasts strongly argue for a prominent role of the mesenchyme in BCC development and invasiveness in NBCCS.
Often the microarray experiments were performed with a small number of biological replicates, and this presented problems for detecting differentially expressed genes while avoiding concomitant high false positive rates (Wei et al., 2004).
On stimulation of TLR-4 with LPS, I κB- α is phosphorylated by I κB- α kinase and thus phosphor-I κB- α is transiently expressed in the cytoplasm concomitant with a similarly transient decrease in cytoplasmic I κB- α (Aggarwal, 2004).
The investigator reviewed the completed diary with the patient to ensure that all required information had been registered, recorded vital signs and concomitant treatments and expressed a global assessment of tolerability.
Numerous data in the literature have already reported that some cytoskeleton constituents are expressed in epithelial cells with concomitant acquisition of new morphological and migratory phenotypes, a phenomenon called epithelial-mesenchymal transition.
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