Recently, we determined expression of seven different phosphorylated residues on ERα in breast cancer samples from patients who subsequently were treated with tamoxifen, and found that multiple tumors expressed combinations of phospho-ERα epitopes [ 6].
To corroborate the association of BACE1 with the anterograde trajectory of axonal calsyntenin-1/APP/BACE1 vesicles we expressed combinations of fluorescently tagged calsyntenin-1, APP, BACE1 in cultured hippocampal neurons and tracked their vesicular migration along axons by live-imaging.
Previously, we had determined expression of seven different phosphorylated residues on ERα in these same breast cancer samples from patients who subsequently received adjuvant tamoxifen therapy, and found that multiple tumors expressed combinations of phosphorylated ERα epitopes [ 5, 6].
In addition to the usual set-theoretic operators, configuration logic is equipped with a coalescing operator + to express combination of configuration sets.
Our method allows the detection of small spectral variations in depth in the living brain, which is essential for imaging efficiently transgenic animals expressing combination of multiple fluorescent proteins.
Immunization with rAd vectors expressing combination of HA from H1, H5, H7, and H9 induced high levels of stem-specific neutralizing Abs and conferred protection against virus replication following challenge with antigenically distinct viruses from these subtypes [ 142].
Together the data presented here will enable the construction of new expression cassettes that express combinations of molecules for therapeutic purposes.
The effects of variations of 3-HB precursor pathways on PHB accumulation were investigated by expressing combinations of C. necator PHB pathway genes.
Normalized fluorescence divided by OD600 as a function of aTc for cells expressing combinations of T7-U or T7-P and mCherry-U or mCherry-P following 8.3 h of induction with 1 mM IPTG (bottom).
By expressing combinations of different N-methyltransferases, we were able to demonstrate re-direction of flux to an alternate pathway and develop strains that support the production of diverse methylxanthines.
