The breadth of expression of a gene, namely whether it has tissue-specific expression or is expressed broadly over more tissues, has been shown to be correlated with several patterns of molecular evolution (e.g. [ 36- 40]).
The antibody staining pattern confirmed the caps-lacZ expression pattern: Trn is expressed broadly in the morphogenetic furrow and in subsets of ommatidial cells after the furrow (Fig. 2D).
Expression of Rnf32, however, does not reflect the Shh expression pattern but is expressed broadly throughout the embryo at E11.5.
Although Slitrk1 through Slitrk5 are expressed broadly throughout the brain, the expression of Slitrk6 is highly restricted to thalamic nuclei [1].
At this time, Even-skipped2 and Delta expression are turned off and Eve1 is expressed broadly across the growth zone.
Molecular markers of feather patterning, such as CTNNB1 and EDAR, are expressed broadly in sc/sc embryonic skin, but their expression does not resolve into a punctate pattern [ 4, 20], or is only transiently punctate in some regions of the body [ 21], suggesting that the epidermis is unable to participate in pattern formation.
GPR3 is an orphan G protein-coupled receptor endowed with constitutive Gs signaling activity, which is expressed broadly in the central nervous system, with maximal expression in the habenula.
We asked whether genes harboring SCPs were more likely than other genes to have no detectable expression, and whether they were less likely to be expressed broadly (see Materials and Methods).
At the gastrula stage, evx is expressed broadly at the vegetal pole, and as observed with wnt1, its expression becomes reduced to the posterior end of the trunk and anus at the introvertula stage.
SmGA3ox1 expressed broadly in the tissues analyzed, while SmGA3ox2 exhibited more tissue-specific expression with the highest level in stems and roots, followed by leaves, and the lowest in flowers.
Syndecan2 is a member of the Syndecan family of transmembrane proteoglycans, expressed broadly in mammals.
