When co-expressed, the two isoforms were either expressed at the same level or the B isoform was more strongly expressed than the A isoform.
ef1a was expressed at the same level in all libraries (Gene expression data found at https://marineseq.imr.no/salmon/annot2013/).
For each mussel, the results revealed that the pi-class GSTs are expressed at the same level in the three tissues.
They have tested 11 different human adult and fetal tissues and found 47 transcripts expressed at the same level in all the tissues [16].
As previously discussed, it seems unlikely to find genes which are expressed at the same level across all tissues of an organism.
Therefore the different possible combination of interacting proteins, or even the formation of large complexes, was assayed when all of them are expressed at the same level.
Analysis of the heterozygote population R/W in colorectal cancer patients shows that both alleles are expressed at the same level (our unpublished data).
The imatinib dose-response was further examined with the Δ1121 mutant, which showed approximately a 10-fold reduced sensitivity to imatinib when expressed at the same level as BCR63-ABL (Figure 7B).
Another direct target of Gli2 in neural stem cells, Sox2 [67], was expressed at the same level in undifferentiated P19[Gli/EnR] and P19 control cells (Fig. 5, panel Sox2, day 0).
We constructed the Lys42»Ala mutation in Syn-IlvA-1, and found that although this protein was expressed at the same level as the parental sequence, it fails to rescue ΔilvA.
Remarkably, PARP-dBRCT, which expressed at the same level as PARP-WT (Figure 5A), fully reconstituted O/N stress dependent NAD degradation (Figure 5C, top left panel), and TRPM2 dependent Ca2+ transients (Figure 5C, right panel).
