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We did not to make the claim that let-7 overexpression is effective in MYC cancers solely because it is expressed at low doses.
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To compare the effects of CXCR7 to that of a known co-regulator of AR-mediated transcription, AD-LNCaP cells were co-transfected with an expression vector encoding α-actinin-4, a protein that enhances or represses AR activity when expressed at low and high doses, respectively, in mammalian cells [ 53].
Genes expressed at low and higher levels were analyzed separately.
(A ) Expressed at low levels: transcripts expressed at 0.5 2 FPKM, (B ) expressed at high levels: transcripts expressed at 2 10 FPKM.
Whether the reduced values of CD4+62L+ lymphocytes in participants with cumulative doses below 100 mSv express prevalence of Th1 response at low doses still remains an assumption due to incomplete research (haven't distinguished memory and naive cells) but is an important issue for future studies.
The phenomenon that the hypoglycemic effect of BLPs linearly correlated with the dose given at low doses and expressed nonlinearity at high doses may be ascribed to the saturability of biotin receptors on enterocytes.
A similar induction of gene transcription was observed with ectopically expressed CTF, ranging between 100- and 200-fold even at low doses of plasmid DNA.
At low doses of the sensitisers, the sensitisation may be greater in lines expressing low levels of P-glycoprotein than in lines showing high levels.
At low doses, lead exposure is linked to intellectual deficits; at high doses, seizures and death.
Inferences for dose response curves at low doses and dose rates are drawn.
And we know that at low doses the risks are low.
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