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The homozygous line R5 showed downregulation of the analyzed progenitor markers, but only MSI1 was downregulated in the homozygous line R1, and no significant downregulation of the progenitor markers was evident in the WT line (data not shown), which indicated that neural progenitor markers were expressed at a steady level despite attempts of differentiation in some lines.
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This revealed that S10A was expressed at a higher steady state level than WT Puma.
Mr. Barron played a steady boil of bright ideas, all expressed at a level dynamic.
Under these conditions, deterministic analysis using rate equations shows a single steady state, in which both genes are expressed at a low basal level.
Transcription factors are often expressed at low steady state levels, of the thirty-eight LTTRs we examined, only two had detectable peptides in a mass-spectrometry based catalog of protein abundance in E. coli [23].
These results verified that GAL1pro:: a1 was expressed at steady state and was largely insensitive to Sir-based silencing.
We also detected novel palmitoylated proteins expressed at steady state, and validated several of these proteins, including T-lymphocyte activation antigen CD86 and Toll-like receptor 2 (TLR2) in dendritic cells (DCs), and E3 ubiquitin-protein ligase NEDD4 in MEFs.
The enrichment in specific biological processes was calculated in pancreatic αTC1-6 versus βTC1 cells subnetworks (networks made of genes regulated by miRNAs specifically expressed at steady state in αTC1-6 and βTC1 cells, respectively) (Table 1).
In fact, besides being specifically expressed at steady state in α cells (αTC1-6), but not in β cells (βTC1 or INS-1), both miRNAs were significantly co-expressed and downregulated in αTC1-6 during a time-course treatment with cytokines, compared to matched untreated controls (see Figures 2A and 2B, Additional file 6).
Interestingly, Microrna.org predicts two binding sites for mmu-miR-296-3p mmu-miR-296-3p mmu-miR-296-3p mmu-miR-296-3pf 73 miRNand mmu-miR-298-5p mmu-miR-298-5p mmu-miR-298-5p mmu-miR-298-5p αTC1-6 with respect tonβTC1, have validated targets known to be expressed in Mafbalian pancreatic α cells (see link to T1Dbase in mRNArials and Methods).
Macaques may encode as many as 30 distinct MHC class I transcripts expressed at widely differing steady state levels in peripheral blood.
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