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In gastrointestinal SMCs, a mixed population of muscarinic receptors (M2 and M3) with the predominance of the M2 subtype (75 82%) are co-expressed (reviewed in Refs. [62 64]).
There are two classes of histones, namely canonical histones and histone variants (known as replacement histones); canonical histones are encoded by genes that are expressed in a DNA-replication-dependent and S-phase-specific manner, whereas the replacement histones are encoded by genes that are constitutively expressed (reviewed in [ 1]).
It is very likely that tissue specific transcriptional regulators, such as enhancers/repressors and transcription factors control miR-125b expression [ 79] that can have particular consequences: By now it is very well appreciated that miRNAs function by repressing target mRNAs that should not be expressed (reviewed in [ 77]).
CXCL12 stimulates angiogenesis directly by acting on ECs, as they express CXCR4 (reviewed in Salcedo and Oppenheim).
It is generally accepted that statistical testing is required to reliable identify differentially expressed genes (reviewed in eg, Allison et al. 14).
Also during metastatic dissemination, CXCR4-expressing metastatic cells home to organs that express CXCL12 (reviewed in Burger and Kipps).
In mammals, they are CpG rich and are usually found in constitutively expressed genes (review by Lenhard et al. [ 14]).
In that context, it is worth mentioning that 70%to90%0% of primary breast tumors express the AR (reviewed in [ 56]).
Crystallin proteins often have been co-opted during evolution when enzymes used for other purposes have become expressed in eyes (reviewed in Piatigorsky 2007).
Fscn1 (fascin-1), an actin-bundling protein highly expressed in brain (reviewed in [44]), was downregulated in both homozygous CbCln3Δex7/8 and homozygous CbCln6nclf cells (Tables 1 and S3).
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