Increasing HP1α expression in cells that normally express little of this protein decreased invasiveness, whereas decreasing the expression of this protein by RNAi in cells otherwise replete with HP1α increased their invasiveness (Norwood et al. 2006).
Furthermore, in breast cancer, tumorigenic but nonmetastatic breast cancer cell lines express little or no miR-10b, which downregulates HOXD10 expression, in keeping with high HOXD10 expression (Ma et al, 2007).
In contrast to our findings related to NOD2, our data indicated that uninfected brain tissues express little or no NOD1, and only a modest level of expression was detectable following infection with the gram-positive bacteria S. pneumoniae.
Importantly, it has been determined that over 70% of estrogen receptor alpha (ER) negative breast cancers express little or no WWOX protein, suggesting an inverse association between WWOX expression and increasing breast cancer aggressiveness [ 8, 9].
During this change, or dedifferentiation, the expression of type I and type III procollagen is induced where normal chondrocytes express little type I and type III procollagen.
The breast cancer cell lines SKBr3 and MDA-MB-231, which express little endogenous ARHI, were used to examine the effect of ARHI re-expression in cell culture.
Peers express little surprise.
But they adjusted and express little nostalgia for Washington.
Most who do qualify express little interest in signing up.
Many, however, express little confidence in the legal system, describing it, at best, as chaotic.
Was he in the debate?" Trump's fans tend to express little regard for political norms.
