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To address this question, we first explored whether treatment with GW501516 also impacted gene expression in human activated HSC LX-2 cells, which express key genes for hepatic fibrosis and are phenotypically similar to primary activated human HSCs in vivo[ 17].
In some cases, this results from deliberate attempts to translate the vision of designers and marketers into a product that can help consumers express key aspects of their identity.
Analysis of the transcriptional profiles of these LNSC subsets indicated that SCs express key immune mediators and growth factors, and provided important insights into the lymph node conduit network, FRC-specialization, and the DNC identity.
Our findings show that R28 cells express key neuronal markers calbindin, protein kinase C and the microtubule associated protein-2 (MAP-2) by confocal immunofluorescence which has not been shown before, but also calretinin which has not been reported previously.
Subpopulations of neurons located in the ventromedial part of the ARC express key neuropeptides controlling feeding behavior.
These results show that embryonic tissues express key circadian genes and have the capacity to express active circadian regulatory cycles.
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Here we show that under severe hypoxia, gene expression of ubiquitously expressed key enzymes and transporters in folate metabolism and nucleoside homeostasis is downregulated.
Second, OSKM and OSKMV donor cells expressed key premeiotic germline markers with specific expression of the early spermatogonial marker, GFRα1 limited to OSKMV cells only.
3) The authors rely on transgenic flies expressing key centrosome proteins tagged with fluorescent proteins where expression levels may alter their dynamics and/or their distribution.
Cells on nanowire surfaces expressed key neuronal markers and demonstrated neuronal phenotypic behavior as compared to the cells on control surfaces.
Although significant progress has been made in improving plant immunity by expressing key, defense-related genes and proteins from different species in transgenic crops, a challenge remains for molecular breeders and biotechnologists to successfully engineer elite, transgenic crop varieties with improved resistance against critical plant pathogens.
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