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Finally the tree introduces the four groups of combined exposures (I, II, IIIA, and IIIB) and the MCR/HI plot as a tool for organizing and presenting combined exposures data and how exposures vary across individuals in an exposed population.
However none of these tissues contained detectable levels of the TTC4 protein even after extended exposures ( data not shown).
However, we observed some DTT-resistant signals in non-monomer areas in images with long exposures (data not shown).
We did not observe proteolysis of any of the Apobec 3 proteins incorporated into XMRV particles (Figure 1A), even after longer exposures (data not shown).
HCT116 cells consistently bound, as well as processed into larger-MW bands, radioactivity from all three 32P-labeled peptides (MA11, MA20, and MA22) at a much lower rate than Caco2 and HCT15 cells, but incorporation into HCT116 cellular proteins was eventually visible on longer exposures (data not shown).
For some exposures, data are available to examine dose effect.
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Animal data are deemed not relevant, human data not representative, and exposure data not reliable".
But the study has considerable strengths in measuring frequency and duration of smoking and in collecting exposure data by biochemical analysis as well as by repeated interviews.
Dose estimation from clinical exposure data (10 60 patients recommended).
Exposure data of marine and freshwater species to microplastics.
Currently, there are limited "real-world" exposure data.
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