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The currently projected goal of toxicity assessment is to determine the threshold level of exposure triggering inflammation in the lung.
Therefore the higher induction of CAT activity seen here could be due to 24 mM DCA exposure triggering similar peroxisome activity increases in L2 cells.
First, subclinical gut inflammation might lead to increased gut permeability and prolonged antigen exposure, triggering more severe disease as evidenced by higher BASDAI scores and more functional disability as evidenced by higher BASFI scores.
Interestingly, in line with the multifactorial nature of ALS, a recent modelling study by Al-Chalabi and colleagues suggests that in ALS, an underlying genetic susceptibility occurs in combination with environmental factors, which culminates in up to six exposures with the final exposure triggering the onset of disease [ 21].
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However, high glutamate exposure triggers neuronal death, a process known as excitotoxicity.
Cr6+ exposure triggered a 579% increase in the number of erythrocytes containing micronuclei, a frequently used marker of cellular toxicity.
Dynamic light scattering analysis revealed that tBLM exposure triggered minor coalescence for bare and amine-functionalized silica nanoparticles but not for carboxyl-functionalized silica nanoparticles.
It has recently been demonstrated that AS2O3 exposure triggers the nucleoplasmic PML transfers toward the nuclear matrix and nuclear body (NB) (Jeanne et al., 2010; Goto et al., 2011).
These results indicate that HMF exposure triggers an acceleration of NS growth in primary cultures from both young and adult mice brains, and promotes formation of NSs from the adult hippocampus.
Moreover, capitalizing on the fears of public exposure triggered by Birkenfeld's disclosures, the IRS last year offered a limited amnesty for Americans ready to fess up to their previously undisclosed offshore accounts.
The public exposure triggered online abuse from anonymous commenters who claimed Overbey concocted the incident in order to receive a payout.
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