We tested this with mRNA injection followed by exposure to protocol sH(1.5d:38h) without hPC, and we found that embryos with irs2 or btr01 overexpression showed improved survival.
We then reasoned that if the 70 80 Hz response to odours is a trace of higher order olfactory processing, it should change upon exposure to olfactory protocols that might change the value of the olfactory stimuli being presented to the fly.
Railway workers with diverse occupational traits from both manual and administrative sectors involving locomotive engine pilots or drivers, railroad yardworkers, trackmen, maintenance workers, signalers, station masters, shunters, and office workers were predominantly classified as high strained workers because of their prolonged exposure to rigid protocols and limited rests [ 34].
Fellows and residents might have been influenced by direct exposure to the protocol or by exposure to colleagues at the other hospital, and all trainees, I expect, were exposed to common teaching.
Previous work by our lab demonstrated that repeated exposure to WBV using protocols that model those used clinically, induces intervertebral disc (IVD) degeneration and osteoarthritis-like damage in the knee of skeletally mature, male mice of a single outbred strain (CD-1).
We, therefore, counted the number of regenerative crypts per unit area of intestinal cross section, 3.5 days after exposure to WBI, according to protocols originally described by Withers and Elkind [26].
Upon exposure to the degradation protocol particle size increased, the electrochemical areas (ECAs) of the catalysts decreased, the catalytic layers became thinner, and the average pore size decreased, indicating both carbon and Pt corrosion.
These findings confirm previous findings of high anxiety level of JS rats even 1 month after the exposure to the stress protocol [19], [20].
Nevertheless, experiments limiting exposure to the CPS protocol to early or late gestation or early postnatal life may allow us to determine the stages of development most susceptible to the insult.
We had hypothesised that exposure to the CPS protocol, and the significant circadian disruption that this creates, would significantly impact on the developing fetal SCN with consequences for rhythmicity as adults.
