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CO is a known neurotoxin, and there is a potential for chronic exposure to exert neurologic effects.
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A recently published study indicated that PAH exposure appears to exert the greatest adverse effect on fetal growth during the first trimester [ 13].
Infusional 5FU and oral agents, which give similar continuous exposure are thought to exert antitumour effect through TS inhibition, as opposed to short exposure to bolus 5FU, which targets RNA synthesis (Aschele et al, 1992).
However, it is important to note that since Treg cells require exposure to antigen to exert their full suppressive function, estrogen alone would be insufficient to activate Treg cells for pregnancy, and instead can be viewed as potentiating Treg cells in preparation for stimulation by pregnancy-associated antigens.
Exposure to hyperoxia exerted a toxic effect with induction of cell death and reduced cellular proliferation in several cell types, such as human lung microvascular endothelial cells and bovine adrenal capillary endothelial cells [26, 27].
The present data suggest that lifetime exposure to smoking exerts an effect on reducing bleeding on probing.
In articular tissue, fibrinogen exposure has been shown to exert proinflammatory functions.
These findings therefore indicate that the induction of CTL function in MLR was suppressed by asbestos, and it was found that asbestos exposure has the potential to exert a suppressive effect on CTL induction following antigen stimulation.
In order to determine the minimal exposure time required by CNF1 to exert its effects, cells were treated with CNF1 (18 nM) for different times (ranging from 1 up to 16 hours).
Exposure to 1600 μg/ml was found to exert a minor cytotoxic effect on ARPE-19 cells.
We also found that an initial short exposure to CN-A was enough to exert the combined effect.
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