Sentence examples for exposure to act from inspiring English sources
Although it has been documented that hepatic apoptosis is not always associated with DNA fragmentation [ 24], typical DNA ladder was shown with agarose gel electrophoresis which provided additional evidence in support of cell apoptosis after exposure to Act D/TNF-α.
Also consistent with known inputs of signalling on neural development (Andoniadou and Martinez-Barbera, 2013; Turner et al., 2014c), Sox1 GFP expression was suppressed by exposure to Act, although a few foci of expression remained in some aggregates (Fig. 6 and Fig. 7A).
In the presence of food, exposure to ACT-333679 was decreased by 27%%.
The exposure to ACT-333679 was approximately fourfold higher than with selexipag.
This hypothesis is supported by the observation that the exposure to ACT-132577 after continued dosing (day 12) was very similar to that without rifampin.
OATP is unlikely to be involved in the initial increase of exposure to ACT-132577 based on the fact that concomitant treatment with Cs, also a major inhibitor of OATP, did not show the same effect.
Although the exposure to ACT-132577 at steady-state was not affected by concomitant treatment with rifampin, the approximately four-fold reduction in exposure to macitentan in the presence of rifampin might affect the overall pharmacological effect of the drug.
This will, at least, reduce the exposure to ACTs caused by presumptive malaria treatment as noted in the present study.
In a similar comparative cross-sectional study with Persian-speaking refugees, it was not length of time in detention but 'stressful' experiences in detention (e.g. exposure to acts of violence, not receiving adequate medical attention etc).
We also noted that women reported exposure to acts considered to be "severe"; for example, being "slammed against the wall," "grabbed," "burned or scaled" and "choked" more often than men, which is consistent with previous findings indicating that men use serious assaults to a larger extent than women [ 14].
However, these risk factors would have to be associated with TTHM exposure levels to act as confounders that is, they would have to be varying over time in concert with the variation of TTHM levels.
