Sentence examples for exposure scheme from inspiring English sources
By establishing direct correlation of ultrasound-induced bubble activities with intracellular uptake and pore size, we designed a ramped pulse exposure scheme for optimizing microbubble excitation to improve sonoporation gene transfection.
The exposure scheme consisted of a "high" and a "low" dose for each compound, and the corresponding combinations.
Our animal model and exposure scheme were initially chosen to evaluate the effects of perinatal BPA exposure on the mouse epigenome (Anderson et al. 2012) and on adult obesity risk (Anderson et al. 2013), rather than on liver tumorigenesis.
Using a lifelong exposure scheme, we found significant alterations of reproductive development and impairment of several fertility end points by these compounds, the most severe effect resulting from combined exposure to a dietary level of genistein and a level of vinclozolin lower than the U.S. EPA-proposed NOAEL.
Doubts about the exposure scheme were raised in a Health and Safety Executive HSEE) criteria document, which reported that the "arithmetic mean exposure was approximately 22 ppm" and that "a significant proportion of workers would have been exposed to average concentrations of approximately 50 ppm" (Cary, 1995).
The individual steady-state values reached after different dosing schemes give rise to a human:rat steady-state-based margin of exposure (MOE) ratio range of 0.33 0.44 and a human:rat AUC-based MOE range range of 0.33 0.37 for pharmacokinetic extrapolation with respect to the dietary exposure schemes assessed.
The significant increase in proliferation observed in our study, but not in other studies, may be a function of differing BPA exposure schemes or routes of administration (i.e., postnatal vs. prenatal exposures, oral administration vs. subcutaneous implants, dose, etc).
We also showed the effect of different exposure schemes, varying from a specific concentration continuously throughout the entire selection to shifting from one concentration to another higher one later and back to the original concentration again.
Tilt series were collected from −60° to 60° with an angular increment of 2° and an exposure time scheme of 1/cos of the tilt angle.
We used three exposure classification schemes: median (low, high), tertile (low, medium, high) and quartile (low, medium, high, very high).
Our study found no "dose response" between the number of years of exposure to the scheme (enrolment in the scheme) and the risk of overall mortality, and no significant association between risk of overall mortality and areas covered by the scheme.
