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Exposure schedule (intermittent, continuous or ad libitum).
The U.S. Food and Drug Administration is considering changes to its regulations that involve the content and design of its warning labels, a re-definement of who is a manufacturer, an updating of the recommended exposure schedule, an updating of the value of minimal erythemal dose (MED), and possible use of the non-melanoma cancer action spectrum for calculating recommended annual dose limits.
For this group, the administrations of DEN, 2AAF and PH were carried out before ELF-EMF exposure schedule.
The SN38 sequence was applied for 24 h, starting either 48 h before LOHP-FA (schedule A), or just after LOHP-FA exposure (schedule B).
There are no equivalent experimental asthma studies with which to compare these responses directly, because the ETS/OVA exposure schedule we followed has not been reported previously in a mouse model of asthma.
Exposure schedule of FR consisted of 2 Gy of X-rays every 24 h up to 5 days (total 10 Gy) and AR consisted of exposure to a single dose of 10-Gy X-rays.
Similar(54)
A particular study could include both positive and negative findings, if more than one experiment was performed with varying cell lines, exposure schedules, etc., or if more than one biological endpoint was measured.
Concentration ranges of 0.01-1.0 microM and 0.0001-1.0 microM were used in short- and long-term exposure schedules respectively.
These practices may converge, and both risk factors may be alleviated with innovations taking advantage of light exposure schedules.
Preclinical data and some clinical data support the use of prolonged exposure schedules of camptothecins (Furuta and Yokokura, 1990; Houghton et al, 1995; O'Reilly and Rowinsky, 1996).
Using simultaneous or sequential exposure schedules, the cytotoxicity and radiosensitising effect of 24 h MTA combined with 1 h or 24 h dFdC were analysed.
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