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A radiation biology experiment was performed in the research room of the proton therapy facility at Loma Linda University Medical Center to simulate the proton exposure produced by a solar particle event.
If all this suggests an impossibly self-critical eye -- not to mention superhuman endurance -- consider that Mr. Wesely intended to make only eight images, each a nearly three-year-long exposure produced by cameras he had set up and then essentially left to their own devices.
The lower drug exposure produced by the Mylan ER is probably due to the water dependent passive diffusion release mechanism of the pellets.
The results got from the research supported that imatinib exposure was related to hematologic response; thus an increase in imatinib exposure produced by apigenin is likely to be clinically relevant and may lead to adverse drug reaction.
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In silico models suggest that exposures produced by infusions of β-lactam antibiotics generate a greater probability of target attainment than those attained with bolus dosing (13).
However, the combined exposure produced more severe effects by both additive and synergistic mechanisms.
Mutant frequencies obtained were 10 times higher from the chronic exposure than produced by a nearly lethal acute dose.
Aircraft noise data were obtained from aircraft noise exposure forecasts produced by Vancouver International Airport Authority (Gan et al. 2012).
Although five iterations are insufficient to generate a reliable sample for propagation of uncertainty, we find the plots helpful for visualizing the complex exposure patterns produced by our three-level uncertainty factors (U1, U2, and U3).
The exposure misclassification produced by such methods may lead to bias in estimating the effects in subpopulations and overall and may adversely affect standard error estimates (Gryparis et al. 2009; Kim et al. 2009; Szpiro et al. 2009).
There is also recent evidence that the cellular-level memory of high fetal/neonatal androgen exposure is produced by androgen-dependent epigenetic changes (including both histone tail modifications and DNA methylation) that modulate gene expression independent of the DNA sequences of genes and their regulatory elements (reviewed in 25).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com