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As well as facilitating the exposure of errors, the requirement to deposit the data supporting research papers should also create an additional hurdle for fraudsters.
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Single-site time-series studies have been criticized because of exposure measurement errors, substantial variation of the air pollution effects and the heterogeneity of the statistical approaches used in different studies [ 13].
These additional microenvironmental measurements can be used for fitting models to better estimate exposure, for model validation, and for assessment of errors in exposure assignments.
Such an evaluation of multipollutant patterns is important to better understand the magnitude of exposure assignment errors when using a single pollutant, the potential impact of such assignment errors on exposure effect relationships and to ultimately understand the full effect of complex mixtures (Billionnet et al. 2012).
The ignorance of these factors undoubtedly contributed to exposure measurement errors, of which direction and magnitude might differ depending on the air pollution metrics used [ 30].
In addition, we used a Monte Carlo sensitivity analysis to assess the potential effects of exposure measurement errors on study estimates.
The impact of exposure misclassification errors on heat effects remains unclear.
We have confirmed the previously reported lack of effect of exposure measurement error on the ratio estimate of interaction [ 36], but reveal that the coefficient estimate is biased towards the null in the scenarios considered.
We simulated the relationship between water chloroform concentrations and chloroform uptake in pregnant women to assess the potential extent of exposure measurement error in epidemiologic studies of the health effects of exposure to water disinfection by-products.
Because of the prevalence of exposure measurement error in epidemiological data, conclusions about the linearity of the exposure-response curve must be examined carefully and treated with some skepticism.
There are several general problems in environmental epidemiology : long latent periods, low-level exposures, errors of exposure measurement, small effects….
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