Three separated experiments were conducted, one with each chemical, with each experiment designed to measure both the effects of exposure on a range of life-history traits and also to obtain a sample of exposed nematode for transcriptional profiling (see Fig. 1 for schematic of experimental design).
Although rates of post-traumatic stress disorder were comparable across all three clinical groups, hoarders (regardless of the presence of comorbid OCD) reported greater exposure to a range of traumatic and stressful life events compared to the two non-hoarding groups.
After 1 h of exposure to a range of concentrations of cisplatin, the cells were washed with PBS and incubated in fresh medium for 24 h.
Respondents were asked about their social and demographic characteristics, the presence of respiratory symptoms and frequency of exposure to a range of pollution types.
The Negative Life Events Scale (NLES) has been included in nationally representative surveys of the Indigenous and Australian population since 2002 as a measure of exposure to a range of 'life stressors'.
Using the SRB cell proliferation assay, the growth of BxPC-3 and MIA PaCa-2 cell lines was measured after 24, 48, and 72 h of exposure to a range of concentrations of either AR-18, gemcitabine, or a concurrent combination of both drugs; using either a fixed ratio of 200 1 AR-18 to gemcitabine, or variable doses of both drugs.
A study in BMC Genomics applies this approach to investigating the effects of exposure to a range of xenobiotics on changes in gene expression in the larvae of Aedes aegypti, the mosquito vector of dengue fever.
Studies predating the formulation of the TDS hypothesis often were designed to explore the association of in utero exposure to a range of pharmaceuticals with birth malformations.
Also, in an immortalised normal fibroblast cell line NB1-Tert transfected to overexpress the artemis protein, we observed increased cellular radiosensitivity in a clonogenic assay following exposure to a range of doses of gamma radiation.
To characterize the effects of H2O2 in inducing cell death of HUVECs, we assessed morphological changes 12 h after exposure to a range of doses of H2O2 (0.1 mM, 0.5 mM and 1.0 mM).
