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Our findings of increased exercise symptoms in response to fine PM exposure may be attributable to increased minute ventilation and an increased dose of fine PM in the distal airways and the pulmonary circulation that is more potent in eliciting exercise-related symptoms than the doses of coarse PM that deposit in the more proximal airways.
Neurological consequences of lead exposure may be attributable to direct neurotoxic effects on the vascular system, including hypertension and cardiovascular disease, or through effects on diabetes and poor renal health (Menke et al. 2006; Navas-Acien et al. 2007; Schober et al. 2006; Weisskopf et al. 2009).
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The negative finding of the association between systolic BP and 1-year air pollution exposures may be attributable to a much larger effect of traditional risk factor, for example, age, on systolic BP than 1-year air pollution exposures among our study subjects.
Exposure misclassification may be attributable to the use of a model for exposure assessment (even with bias correction), the use of ambient rather than personal data, the use of a single residential point rather than a profile of where a woman's time is spent, and the assumption that residence at birth was unchanged throughout pregnancy.
It is plausible that larger magnitudes of association between long-term exposure and mortality may be attributable to cumulative effects that increase the sensitivity of highly exposed population subgroups.
Failure to find consistent evidence of a link between residential exposures and adult cancers may be attributable to exposure misclassification.
On a population level, approximately 1 in 11 cases of COPD may be attributed, at least in part, to home ETS exposure; 1 in 15 cases may be attributable to workplace ETS exposure.
It was considered that the fall in lung function seen after exposure to cotton dust may be attributable in part to the activity of arachidonic acid metabolites, such as leucotrienes as well as to the more established release of histamine by cotton dust.
These differences in response between HT29 and HCT116 following simultaneous exposure to the drug combinations may be attributable to the p53 status of the cells.
Thus, lack of findings of interaction with air pollution and participation in sports may be attributable to exposure misclassification.
Gulf War syndrome, which some have hypothesized may be attributable to exposure to an OP agent (Golomb 2008), has also been associated with low PON1 ARYase (Haley et al. 1999) and POase (Mackness et al. 2000) measurements.
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