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Table 3 shows the mean of the exposure log odds ratio estimates across the 10,000 repetitions, the mean standard error, and the percent bias for each mechanism.
With missingness dependent on outcome (mechanism 2), the average estimates of the exposure log odds ratio were again close to the full data estimates.
This meant that among the complete records, the mean age of persons who died was reduced in comparison with the full data, and consequently the exposure log odds ratio estimates were dominated by the associations among the younger crew, which, as previously noted, were larger.
In a study by Chen Y et al. (2011), results suggested a higher cardiovascular mortality rate with exposure to drinking water arsenic concentrations > 12 μg/L, and an increasing trend in hazard ratios (HRs) with increasing arsenic exposure (log rank trend test = 0.0019) while controlling for known CHD risk factors.
These include an RR model that is linear in exposure throughout the global concentration range (Lin), a model that is linear up to 30 μg/m and constant above 30 μg/m (Lin30), a model that is linear up to 50 μg/m and constant above 50 μg/m (Lin50), and a model that is a function of the logarithm of exposure (Log).
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Figure 1 presents the Kaplan Meier estimate of event-free survival for children with B-precursor ALL, stratified by 24-h TWA MF exposures (log rank test P=0.54).
We considered several exposure metrics: cumulative exposure (log-transformed and untransformed), duration of exposure (log-transformed and untransformed), peak exposure, and average exposure (cumulative exposure divided by duration of exposure).
Authors of the update also analyzed cumulative exposure, log-cumulative exposure, and average exposure and applied various lag times (no lag, 5, 10, 15, and 20 years).
The exposure log-odds ratio for study k is denoted β k, the confounding log-odds ratio is denoted γ k, and the α k are the study-specific intercepts.
To study the mechanisms regulating G2/M cell-cycle checkpoint response after IR exposure, log-phase growing MCF-7 cells were exposed to IR at the indicated doses and analyzed for DNA content at 8, 16, and 24 hours after IR.
Second, RDSR was not available for the preceding imaging platform, thus manual exposure logging had to be performed for all patients undergoing TACE on that platform and the DSA radiation time was calculated retrospectively using the number of images acquired during each DSA run.
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