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Family structure influenced exposure (job) assignment for men and women; single mothers were more likely to be blue-collar workers than were other women.
Job strain was modeled as a binary exposure (job strain vs. no job strain [the reference]) and in sensitivity analysis as a categorical variable (high strain, active, passive, and low strain [the reference]).
In particular, neither duration of employment, duration of exposure, age at first exposure, year of first of exposure, job category, cumulative exposure, frequency of peak exposures, nor average intensity of exposure had any effect on kidney cancer or leukemia mortality.
We used a validated and harmonised exposure, job strain [ 7], and register-based COPD outcomes, which have good coverage and which are generally not prone to recall or other biases [ 8]–[ 10].
We then made adjustment for the other work exposure (job demand/control), followed by childhood factors (mother's and father's education, parents' interest in study member's school at age 7 and cognitive ability at age 8), then adult confounders (occupational class at age 43 and BMI, smoking history and level of physical activity at age 60 64) and finally for all covariates simultaneously.
Similar(55)
Among patients reporting VDGF exposure, job-exposure matrix (JEM) analysis found that 61% were exposed to mineral dusts, 34% to biological pollutants and 73% to gas, vapors or fumes.
If true, there would be greater exposure misclassification among lower exposure jobs than higher exposure jobs.
Three experts assigned exposure scores of 0 = no exposure, 1 = low exposure, or 4 = high exposure for 202 (11%) low exposure jobs and 27 (1.5%) high exposure jobs.
The only apparent difference is the rating of high exposure jobs.
We suggest actual EC data might be applied for ranking individual jobs instead of simply assuming that all high exposure jobs have 4 times more exposure to EC than all low exposure jobs.
However their assessed diesel exposure is inconsistent with higher lung cancer risk associated with lower exposure jobs.
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