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A wide surgical exposure is needed with identification of the sciatic nerve.
Meticulous assessment of sunlight exposure is needed especially in women, since self limited public sun exposure may be prevalent among overweight or obese females.
This has limited the use of such technology in pre-clinical research where prolonged and constant exposure is needed to validate targets with less-than-ideal tool compounds to enable a data driven decision without significant upfront investment.
Assessment of geographic and seasonal exposure is needed for identifiying this polymorphic exotic disease.
A lower cPAD indicates that a lesser exposure is needed to induce a toxic effect.
Hence, further research on healthy tissue damage caused by long-term Pt exposure is needed.
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A much larger sample size and information on period of pathogen exposure are needed in future gene environment interaction studies.
A much larger sample size and better characterization of environmental risk exposure containing information on type, intensity and period of pathogen exposure are needed in future studies.
However, due to the high Pb concentrations used in this study further investigations at Pb concentrations closer to human exposure are needed to verify the results.
Results from foods sampled in different seasons suggested that seasonal variability within an individual may contribute notably to overall variability measured in a population and more future studies with longer-term investigation on food ingestion and pollutant exposure are needed.
However, post-approval trials with extensive patient exposure are needed to generate knowledge of more patient-specific clinical effectiveness and long-term safety, in particular with respect to rare adverse reactions.
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