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To develop an operational method for identifying workers potentially exposed to manufactured nano-objects and their aggregates and agglomerates (NOAA) and assessing their potential exposure in frame of epidemiological surveillance program EpiNano.
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Shift in frame of reference.
The over exposure in the frame from nighttime driving and the slight under exposure in the daytime frame is a result of a compromise between the two lighting conditions.
Supplementing biomarkers of exposure by markers of genetic susceptibility tends to further frame the effects of exposure in terms of individual biology and, potentially, individual responsibility.
However, we were not able to evaluate the significance of the exposure time frame in this study because of the small differences in the monitoring times.
IF/OF: in frame or out-of-frame.
Both models have been tested in the frame of prospective epidemiological studies, but in a majority of these investigations the measurement of exposure was restricted to baseline assessment.
Second, exposures in culture occupy a time frame of hours to days, whereas exposures in vivo can involve exposure over the entire course of brain development; again, this reduces the apparent sensitivity of in vitro models.
Returning to the time frame of exposure in the carcinogenic process, the null randomized, controlled trials of fiber (Alberts et al., 2000) and fruit and vegetables (Schatzkin et al., 2000) for the prevention of polyp recurrence amply illustrate Zelen's concerns regarding the timing of the preventive intervention in the disease process.
This is valid, since the lane change angles on typical velocities obtained on motorway is quite low due to physical reasons, and hence the change in course in between two exposures (at a frame rate of 3 fps) can be neglected.
The appearance of lipid droplet-like inclusions that is a characteristic sign of MSC differentiation into adipocytes, was clearly visible after 9 hours exposure rather than in the typical time frame of several days.
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