We had exposure distributions, and hence AF estimates, for countries in North America, Europe, and Asia.
Risk assessors are interested in high quantiles of contaminant exposure distributions.
Evaluation of this approach for APIs in surface waters across England and Wales showed good agreement between modelled exposure distributions and available monitoring data.
This paper presents modeling methods used to estimate exposure distributions of chlorpyrifos and diazinon in the residential microenvironment using the database generated in Arizona (NHEXAS-AZ).
As these exposure distributions are generally very asymmetrical, it is difficult to obtain relevant and stable high quantiles in such a context.
By including toxicological and epidemiological information and data on exposure distributions, more representative results can be obtained from utilizing health economic analyses of the adverse effects associated with environmental chemicals.
Determining OA exposure distribution is complex because it is based on the sum of elementary exposure distributions (eight foodstuffs are analysed here), and each one of these is the product of a consumption distribution and a contamination distribution.
Table 1 presents exposure distributions in cases and controls, matched ORs, 95% CIs and p-values.
Most striking were the contrasts in exposure distributions.
I compared exposure distributions derived from empirically derived species-specific, individual-consumption data from the three populations and exposure distributions derived, in part, from summary statistics for populations.
There remain, however, a number of uncertainties in these AF estimates, particularly in the exposure distributions.
