RAP estimates express the impact of a given exposure on the risk of death, by determining the time (in years) by which the risk of death is anticipated for exposed study participants compared with non-exposed.
All 30 exposed study participants were seronegative for H9N2 antibodies.
Exposed study participants were all plaintiffs in a lawsuit.
Thus, a major strength with the Swedish Fishermen's Families studies is the use of a large and relatively highly exposed study population.
On the other hand, a study with an excessive sample size wastes resources and may unnecessarily expose study participants to potential harm.
Individuals ranging from 15 to 78 years of age with at least 10 years of exposure were included as exposed study participants.
Participants enrolled as controls resided in the same areas, denied having such contact, and when possible, were loosely age, group, and gender matched to exposed participants based on an expected final distribution of exposed study participants.
Each of these studies was designed differently and had different comparison groups, and each report conceded that factors such as indirect human or environmental transmission could have exposed study participants who lacked known farm risk factors.
We also conducted meta-analyses stratified by parent exposed, study quality scores (total and major components), exposure window definition, leukemia subtype, exposure index, farm versus other workplace exposure, study design, publication period, and broad pesticide class.
