When cells are exposed to selected environments, some of proteins change their subcellular localization to interact with other proteins.
On the other hand, regulated protein interactions occur when cells are exposed to selected environments such as stress and environmental cue.
Pregnant Wistar rats (n = 24) were exposed to selected doses (55 mg, 80 mg and 100 mg/kg) of quetiapine, equivalent to human therapeutic doses, from gestation day 6 to 21 orally with control subjects.
In order to investigate the mutagenic potential of solar UV radiation, DNA of the Escherichia coli plasmid pUC19 was exposed to selected wavebands of UV radiation (from vacuum UV to UV-A) by use of a solar simulator and space simulation facilities.
To provide experimental evidence for the hypothesis that interplanetary transfer of the genetic material is possible, phage T7 and isolated T7 DNA thin films have been exposed to selected space conditions: intense UVC radiation (λ=254 nm) and high vacuum (10−4 Pa).
Ascospores (sexual propagules of the mycobiont) of the lichens Fulgensia bracteata, Xanthoria elegans and Xanthoria parietina were exposed to selected space-simulating conditions (up to 16 h of space vacuum at 10−3 Pa and UV radiation at 160 nm ⩽λ⩽400 nm), while embedded in the lichen fruiting bodies.
In this study, human breast cancer (MCF7) cells and human epidermal melanocytes (HEM) cells (control) were exposed to selected far infrared light (3400nm, 3600nm, 3800nm, 3900nm, 4100nm and 4300nm) and visible and near infrared wavelengths (466nm, 585nm, 626nm, 810nm, 850nm and 950nm).
To verify which signaling pathway might be mainly responsible for antiproliferative activity of KYNA, HT-29 cells were exposed to selected inhibitors of signaling pathways and KYNA.
During Phase 2 testing, semen samples from 23 patients attending for either routine diagnostic andrology assessment or IVF/ICSI were prepared and exposed to selected compounds.
To further characterize selected compounds identified in the end point cytotoxicity assay, cells exposed to selected compounds were dynamically monitored over 70 hr using real-time electrical impedance as a measure of viable cell number (Xing et al. 2005).
