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In conclusion, the data suggest that minor alterations in the exposed Domain 2 are critical for the autotransport phenotype of SPATE proteins.
GPI-anchored proteins lack a cytosolically exposed domain.
Overall, this study showed that the homolog of the variable surface exposed P120 protein, P120', was subjected to genetic variability in its surface exposed domain despite its low reactivity with patient sera.
This is not surprising since this amino acid is located in the central region of the flagellin, a surface exposed domain that is free to vary far more widely.
Like ubiquitin, the Ubl domain has a β-grasp fold with an exposed domain hydrophobic face comprised of five β-sheets.
The coat protein of Sf6 is similar to that of bacteriophage P22 and is known to include surface exposed domain (a conserved feature specific to P22 like bacteriophages) with an "HK97-like" core [ 32].
Similar(53)
The UV exposed domains can promote L929 cell adhesion and growth.
Human ZnT3 possesses six tyrosine residues, two facing extracellular exposed domains, one in an intracellular loop, and three in the carboxy-terminal domain.
Conversely, the surface-oriented lysine residues of proteins associated with the IM can be differentially modified with dansyl chloride and then extracted after hydrolysis with chymotrypsin or proteinase K to shave off the exposed domains before selective enrichment and LC-MS identification of the labeled peptides (Cirulli et al., 2007).
MICOS is a large machinery, consisting of two dynamic subcomplexes that are anchored in the inner membrane and expose domains to the intermembrane space.
Such a transition may expose domains previously cryptic within the inactive protein.
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