IL-10 has been found to down-regulate the MHC class II export to plasma membrane, probably via inhibition of cathepsin S [32], [33].
DC maturation cannot be characterized fully by the measurement of a few parameters, as is generally performed by examining MHC class II molecule export to plasma membrane, co-stimulation molecule upregulation and cytokine production.
Given large distance between the spleen and the skin, we could anticipate preferential regulation of genes for proteins exported to plasma and body fluids including acute phase proteins (serum amyloids, lysozyme C and transferrin).
Further studies are required to define whether KCNE1 and KCNE3 determine membrane surface expression of Kv12.2 through control of export to the plasma membrane, promotion of endocytic recycling, or a combination of both mechanisms.
Plasma CER is synthetized in the liver and exported to plasma with lipoproteins.
Nicknamed the "Vampire of the Caribbean," Mr. Cambronne, who died in 2006, bled 6,000 sellers who were paid as little as $3 a day and exported 1,600 gallons of plasma to the United States each month, according to an article in The New York Times.
They want an inquiry into why the United States, particularly the federal Food and Drug Administration, allowed the export of tainted prison plasma from Arkansas and Louisiana to Canada in the 1980s.
NIG and SAL may mediate the export of potassium through the plasma membrane down its concentration gradient in exchange for the uptake of protons, and as a consequence cause acidification of the cytosol.
We have recently reported on the mechanisms underlying the "inside-out" signaling of S1P, its export through the plasma membrane, and its interaction with cell surface receptors.
In control cells, tsO45-G-YFP reached the Golgi apparatus after 45 minutes of export, and the plasma membrane within 2 hours (Fig. 5A, Control).
Yap1p recognizes YRE (Yap1p response elements, 5'-TKACTMA-3') in the promoters of genes involved in redox homeostasis and in xenobiotic export at the plasma membrane.
