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Assembly of this RNP governs the balance for nuclear export of different types of HIV transcripts, which is essential for promoting HIV infectious cycle.
Especially in differentiated cells with a high content of very dense heterochromatin but still active gene expression, clogging the paths to the NPCs should variably affect the export of different cargo molecules.
In this study, we show that XPO-1 inhibition using SINE compounds: KPT-185, KPT-205, KPT-225, and KPT-127 reduced, in a panel of PCa cells, XPO-1-dependent nuclear export of different proteins including AR, Foxo3a, and survivin, modulating cell cycle progression through both a G1 and a G2/M-arrest followed by apoptosis.
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The application of BAMs affects exports of different sectors by small margins according to our findings.
Our results define the global network of factors involved in Drosophila mRNA export, reveal specificity in the export requirements of different transcripts, and expose new avenues for future work in mRNA export.
This visualization shows products that are likely to be exported by countries that export Sets of different knives, cutlery sets.
To assess the strength of the nuclear export activity of different fragments of Atx3 protein, or of full-length Atx3, the Rev(1.4 -GFP nuclear export assay, described previously by Henderson and Eleftheriou [42], was used.
This transport receptor helps to export hundreds of different proteins from the nucleus by recognizing a part of their structure called the 'nuclear export signal'.
This treemap shows the share of countries that export Sets of different knives, cutlery sets.
An approach has been developed based on the mass balance of the pollutant to determine the export coefficients of different land use types (Ding et al., 2010).
This plasma membrane-localized transporter mediates export of many different organic anions including oligomycin as well as phospholipids [ 78- 80].
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