Your English writing platform
Discover LudwigExact(59)
NS1 can also interact with splicing and nuclear export factors (Satterly et al., 2007).
Overall, our results indicate that dimer formation is important for NTF2 function and give insight into the formation of heterodimers by mRNA export factors such as TAP1 and NXT1 that contain NTF2-homology domains.
The principal characteristics of these viral mRNA export factors are a nucleocytoplasmic shuttling activity, an RNA-binding domain and the capacity to interact with cellular mRNA export factors.
A characteristic of all known viral mRNA export factors is the presence of an RNA-binding domain.
We also identified the mRNA processing and export factors Dbp5, Mft1, and Yra1 [55], [56], [57], [58], [58].
In budding yeast, the Yra1 protein participates in mRNP assembly and mediates the association of mRNAs with export factors.
For naturally intron-less transcripts, export factors were proposed to be recruited by co-transcriptional mechanism or through some specific sequence elements [11].
The splicing and export factors are lost during mRNA export to the cytoplasm where additional NMD proteins bind to the EJC [7].
It is tempting to speculate that Rps15p interacts with proteins involved in nuclear export of the pre-40S particles, like nuclear export factors or nucleoporins.
Instead, it is now established that herpesviruses encode a conserved gene family whose proteins act as viral mRNA export factors that mediate nucleocytoplasmic transport of viral transcripts [14].
This potential activity of Not4 toward mRNA processing and export factors may regulate modification of their function through mono-ubiquitination or target them for degradation through poly-ubiquitination.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com