Sentence examples for exponential mutation from inspiring English sources

In this article, the exponential mutation is adopted.

The change in population size is assumed to be either linear or exponential and mutations are assumed to occur following a step-wise mutation model (SMM).

It remains to be determined whether mutations in stem cells accumulate in a simple stochastic manner or whether ageing associated exponential dynamics of mutation accumulation occur.

However, it was shown that chronic low doses of exogenous genotoxic stress caused exponential increases in mutation rates at the mouse Dbl1 gene in the intestinal epithelium (Shaver-Walker et al., 1995).

For each mutation, the exponential range of the reconditioning PCR was determined and the number of necessary aliquots for pooling was set by the signal intensities needed for quantification on the gels (data not shown).

We show that the interplay between mutation and exponential amplification through hitchhiking results in a characteristic frequency spectrum of the resulting novel haplotype variation that depends only on the ratio of the mutation rate and the selection coefficient of the sweep.

Although in each environment, small sample sizes were available for testing distributions, overall the null hypothesis of an exponential DFE for beneficial mutation was strongly rejected, and point estimates of the shape of the DFE consistently pointed toward distributions that are bounded to the right (i.e., in the Weibull domain (Fig. 2)).

On the other hand, if the distribution of N es among mutations is exponential with mean N es = −10, then a significant fraction of mutations will fall into the range of selection intensities (i.e., −10 < N es < 0) that will be strongly affected by a 2-fold difference in N e.

However, variation in the DFE of beneficial mutations is also predicted in fitness landscape models when the number of character dimensions are varied, with a right-truncated DFE of beneficial mutations predicted when the number of character dimensions is low, only converging toward an exponential DFE of beneficial mutations when the number of character dimensions is large.

In figure 4, we show the ability of the One Biallelic Marker ABC method to estimate U, α, and β, when the distribution of arising mutations is exponential.

During aging, adult tissue stem cells exhibit impairments in functionality and exponential increases in premalignant mutations driven by cell-intrinsic defects and alterations in the stem cell niche and the blood circulatory environment (Ju et al., 2007; Behrens et al., 2014).