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"We saw an explosion of cases when the housing development exploded," he said.
Dr. Schuchat likened the spread's unpredictability to that of popcorn: one city could see an explosion of cases and overwhelmed hospitals while another saw few.
"That's a stunning number and reflects an explosion of cases," Dr. Thomas R. Frieden, the director of the C.D.C., said in an interview.
But the international medical community's most powerful weapon for raising money is the fear that an explosion of cases in the third world will let divergent strains merge into something incurable and highly contagious that will attack the West.
But as the ranks of American diabetics have swelled by a distressing 80percentt in the last decade, New York has seen an explosion of cases: 140 percent more, according to the city's health department.
This region of more than 900,000 people, isolated from the Russian mainland and plagued by the social and economic ills that came with the Soviet Union's collapse, was the first hit hard by an explosion of cases among drug addicts and has been a harbinger of the disease's spread ever since.
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I find Zika interesting because the factors contributing to the current explosion of case numbers in South America are multidimensional - environmental, political, economic, medical and population health factors are all intersecting to cause this current crisis.
"There's been an explosion of ILSA cases," he said.
One study found that an explosion of Ebola cases stemmed from a well-known healer who had tried to treat the virus and died.
Silent Plague Articles in this series are examining how China is just beginning to cope with an explosion of AIDS cases, many brought about by poor medical practices.
Demand for drugs that treat diabetes is climbing as rising instances of obesity are causing an explosion of diabetes cases globally.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com